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HPLC analysis of mefloquine and its main metabolite by direct plasma injection with precolumn enrichment and column switching techniques
Summary
Type:
HPLC
Application #:
104290
Detection:
UV, 220nm
Conditions:
eluent: 50mmol Na2SO4 pH 2.84 - acetonitrile (66:33)
flow rate 0.5ml/min
temperature 45°C
Authors:
Arnold, P.J. et al.
Source:
J. Chromatogr. 353 (1986) 193–200
Details
Legend: Fig. 2. Influence of addition of phosphoric acid to plasma on extraction yield, B) blank plasma with addition of 25µl phosphoric acid (40% w/v) per 500µl plasma, C) plasma sample containing 200ng/ml
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